NeuroLiaison: NCSE 隐匿性癫痫自动阻断、脑电爆发抑制跟踪与颅内顺应性实时评估

NeuroLiaison Closed-Loop Bidirectional Neural Interface Architecture

ENG motor intent decoding, biomimetic sensory stimulation, and charge-balanced ASIC

Central System: Neural Interface Controller - Bidirectional ENG/Sensory ASIC

Clinical IoMT Nodes

• Transversal Intrafascicular Electrode (TIME)
• Low-Noise Neural Recording Front-End
• Real-Time Motor Intent Decoder
• Biomimetic Sensory Stimulation Engine
• Bionic Limb / Robotic Actuator

Architectural Layers & Regulatory Standards

• Intraneural Micro-Electrode Interface (TIME Array / Longitudinal Intrafascicular Electrodes (LIFE)): Interfacing directly with nerve axons inside individual peripheral fascicles (median, ulnar, and radial nerves).
• Neural Signal Conditioning & Artifact Blanking (Dynamic Artifact Suppression / High-CMRR Bio-Amps): Recording microvolt-level neural action potentials while suppressing stimulation artifacts and muscle EMG cross-talk.
• Intent Decoding & Neural Prosthetic Telemetry (Kalman Filter / Recurrent Neural Networks): Translating decoded firing rates into smooth, proportional prosthetic joint movements in real time.
• Biomimetic Afferent Sensory Stimulation (Charge-Balanced Biphasic Current Stimulation): Encoding fingertip pressure sensor data into patterned electrical stimulation delivered to sensory nerve fibers.

Key Metrics: < 40 ms (Closed-Loop Sensorimotor Latency) | < 1 µV RMS (ENG Recording Amplifier Noise) | 100% (Charge-Balanced Current Injection) | 10 Years (Implantable Silicone Encapsulation Lifespan)